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Are you at risk of a heart attack or stroke?
Understanding How Controlling Your Cholesterol Reduces Your Risk
Adverse Event Reporting and Prescribing Information can be Found at the bottom of the page

CONSIDER YOUR HEART HEALTH:

REDUCE YOUR CHOLESTEROL

Uncontrolled or continuous high cholesterol is a serious risk factor for cardiovascular disease and could lead to a heart attack or stroke.1
You can’t see or feel cholesterol, but it’s there and could lead to an emergency.

What is cholesterol?

Cholesterol is a fatty substance in the blood. You need some cholesterol to be healthy, as it helps your body to generate new cell walls, hormones and bile acids.2 However, too much can build up within your arteries, making them too narrow.3 This can lead to a cardiovascular health emergency.
It includes good and bad cholesterol, apart from other components:
  • High-density lipoprotein (HDL), the ‘good’ cholesterol2
  • Low-density lipoprotein (LDL), the ‘bad’ cholesterol2
Bad cholesterol (LDL-C), together with other substances, can build up in your arteries as fatty deposits, known as plaque.4,5
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RISK FACTORS INCLUDE:10

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High LDL-C
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Hypertension
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Diabetes
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Lack of exercise
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Low HDL-C
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Inadequate fruit/vegetable intake
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Obesity
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Smoking
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Consumption of alcohol
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Psychosocial factors

REDUCE THE RISK OF A HEART ATTACK OR STROKE

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Your cholesterol won’t go down by itself. Reduce the risk of another heart attack or stroke by reducing your bad cholesterol.1
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Do all you can to lower bad cholesterol following a heart attack or stroke. Certain lifestyle changes can help, such as eating a healthy diet, quitting smoking and exercising more.10
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It’s also important that you stay on therapy. Don’t forget to take the medication prescribed by the doctor to reduce the risk of another heart attack or stroke.
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Immediately following your heart attack or stroke is the best time to take action. Reduce your concern by addressing the risk as soon as possible.
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Ask your doctor what steps you can take to address your high level of bad cholesterol and risk of having another heart attack or stroke.
 
 
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YOU ARE NOT ALONE

It’s natural to worry after a heart attack or stroke. But you are not alone in this.
Enlist the support of your family, friends, local patient group and care team. They are there to help you.

IT’S TIME TO TAKE CONTROL DON’T WAIT

Take the right steps to put your health first. Schedule an appointment with your doctor to discuss your cholesterol level. If your numbers are too high despite being on a cholesterol-lowering therapy, talk to your doctor about treatment options that can further lower your cholesterol and risk of another heart attack or stroke.11 Be in control of your health, fully engage in life and reduce the hidden risk of heart attack or stroke.
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HAVE YOU ASKED YOUR DOCTOR…

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AM I DOING ENOUGH?

If you are already suffering from high cholesterol, it is likely that your doctor has prescribed a statin or other lipid-lowering medication. However, this isn’t always enough to lower “bad” cholesterol for some people.
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Even if you are taking a therapy such as a statin, the risk of a heart attack or stroke may still persist.12,13
Talk to your doctor about treatment options that can further lower your cholesterol and risk of an event.
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References

  1. World Health Organization. Raised Cholesterol. Available at: http://www.who.int/gho/ncd/risk_factors/cholesterol_text/en/ Last accessed June 2018
  2. Goldstein, J. L., & Brown, M. S. (2009). History of Discovery: The LDL Receptor. Arteriosclerosis, Thrombosis, and Vascular Biology, 29(4), 431–438. http://doi.org/10.1161/ATVBAHA.108.179564
  3. Hansson, G.K. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352, 1685-1695 (2005).
  4. National Heart Lung and Blood Institute. What is Cholesterol? Available at: https://www.nhlbi.nih.gov/health-topics/high-blood-cholesterol. Accessed: 21 Aug 2019.
  5. Rader D. Nature. 2008; 451:904-13.
  6. Glaglov S. Compensatory Enlargement of Human Atherosclerotic Coronary Arteries. N Engl J Med 316, 1371-1375 (1987).
  7. World Health Organization. Prevention of Recurrences of Myocardial Infarction and Stroke Study The PREMISE programme: country projects. Available at: http://www.who.int/cardiovascular_diseases/priorities/secondary_prevention/country/en/index1.html Last accessed June 2018.
  8. Bhatt DL, Eagle KA, Ohman EM, et al. Comparative determinants of 4-year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis. JAMA.2010;304:1350-1357. Available at: https://www.ncbi.nlm.nih.gov/pubmed/20805624 Last accessed June 2018
  9. Singapore heart Foundation. Singapore Statistics. Available at: https://www.myheart.org.sg/my-heart/heart-statistics/singapore-statistics/ Last accessed July 2019.
  10. Yusuf S, Hawken S, Ôunpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004;364:937-952.
  11. Sabatine, M. S. et al. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. N. Engl. J. Med. 376, 1713–1722 (2017).
  12. Sampson UK. et al. Residual Cardiovascular Risk Despite Optimal LDL-Cholesterol Reduction with Statins: The Evidence, Etiology, and Therapeutic Challenges. NIH. 14(1): 1–10. doi:10.1007/s11883-011-0219-7. (2012).
  13. Wong ND, et al. Prevalence of the American College of Cardiology/American Heart Association statin eligibility groups, statin use, and low-density lipoprotein cholesterol control in US adults using the National Health and Nutrition Examination Survey 2011–2012. Journal of Clinical Lipidology 10, 1109–1118. (2016).